大鼠行为学评价在针刺作用机制研究中的应用

本文从大鼠行为学评分角度综述有关针刺作用机制研究的文献,肯定了针刺在不同疾病动物模型实验研究中的疗效。在实验中要根据不同的目的选择适当的评分方法。本文对运动功能缺损情况的评价、认知功能障碍评价、大鼠情绪评分、大鼠疼痛行为学评分在针刺治疗不同疾病动物模型中的应用进行了归纳总结,并指出现行使用的某些评分方法因自身局限性尚需要改进,而且还应开发更多的评分方法以更好地评价针刺治疗疾病的效果。

Application of Rat's Praxiology Evaluation to Researches on the Mechanism of Acupuncture in the Treatment of Some Diseases

The present paper reviews recent progress about the application of rat's praxiology evaluation in studies on the mechanism of acupuncture in the treatment of some diseases from 1) motor functional impairment evaluation;2) cognition impairment evaluation;3) animal mood score,and 4) pain behavior evaluation.By using different praxiology evaluation methods,the acupuncture curative effect has been confirmed repeatedly in different pathological models.The animal experimental study plays an important role in understanding the mechanisms of acupuncture in the treatment of some common diseases in clinic.However,due to the multiplicity of diseases,and specificity of various phases of a disease,extensive and specific behavior evaluation methods are relatively fewer,some current method terms are still obscure and manual of operations is deficient.Therefore,further improvement of the current behavior evaluation methods and developing more methods with stronger and specific functions aiming at different experiments(disease models) are definitely necessary.