早期乳腺癌临床诊断分析

 目的 探讨早期乳腺癌临床特点,寻找提高早期乳腺癌诊断率的方法.方法 回顾性分析69例早期乳腺癌的临床资料.结果 乳腺局限性增厚42例(61%),可触及结节者仅24例(34.8%);有乳腺增生病史伴增生症状加重者50例(72.5%).钼靶X线单纯钙化27例(39.1%),肿块结节影11例(15.9%).56例(81.2%)超声检出边界不规则低回声结节,78.6%的结节内或周围可测到血流信号.25例通过空芯针穿刺获得诊断,44例由超声或钼靶定位后手术活检确诊.结论 高危因素妇女乳腺增生症状加重、乳腺局限性增厚是早期乳腺癌的重要表现;彩色多普勒超声对早期乳腺癌的诊断价值可能优于钼靶X线检查;及时对乳腺结节、局限性增厚等可疑病灶行组织学穿刺活检或在超声、钼靶定位后手术活检,可提高早期乳腺癌的诊断率.

Diagnosis of early stage breast cancer:clinical analysis of 60 cases

Objective To study the characteristics of early stage breast cancer,thereby developing the method of improving its diagnostic accordance rate.Methods The data of 69 early stage breast cancer patients hospitalized from January 2004 to January 2007 were retrospectively analyzed.Results Of the 69 patients,42 (61%)presented locall thickening of mammary glands,only 24(34.8%)had palpatble nodules.Fifty cases had mammary glands hyperplasia accompanied by exacerbated symptoms.On mammography,only 27 cases(39.1%)presented calcification and 11 cases (15.9%)mass nodule images.Preoperative ultrasound showed irregular boundary low level-echo nodules in 56(81.2%)patients,and blood flow signal within or around the nodules in 78.6% cases.A definite diagnosis was made in 25 patients through hollow needle aspiration biopsy,and in the other 44 patients by operational biopsy after ultrasound localization.Conclusions Exacerbated symptoms of mammary glands hyperplasia or developing local thickening of mammary glands in high risk women always suggest the possibility of early stage breast cancer.Color Doppler ultrasound might have better diagnostic value than mammography for early stage breast cancer.In order to raise the diagnostic accordance rate of early stage breast cancer,it is necessary to perform promptly needle aspiration or operational biopsy after ultrasound or mammography localization in patients with mammary glands nodules or local thickening.