鼻咽癌放疗后并发鼻窦炎的治疗及相关因素探讨

目的:探讨鼻咽癌放疗后并发鼻窦炎的相关因素和治疗方法。方法:回顾性分析45例鼻咽癌患者放疗后并发鼻窦炎的临床资料。结果:45例中治愈22例(48.9%),好转18例(40.0%),无效5例(11.1%),总有效率88.9%。随访期间未发现肿瘤复发者,所有病例未发现手术后的并发症。结论:鼻咽癌放疗后鼻窦炎的发生率极高,鼻窦炎直接影响鼻咽癌放疗的效果。采用鼻内镜下手术并及时开放窦口引流,对放疗后的鼻窦炎具有良好的疗效。

The treatment of sinusitis in patients with nasopharyngeal carcinoma after radiotherapy and the relative factors

Objective:To explore the surgery way on sinusitis with nasopharyngeal carcinoma(NPC) caused by radiotherapy and the relative factors.Method:Forty-five cases of NPC patients with sinusitis caused by radiotherapy were treated by endoscopic sinus surgery in our department from 1998 to 2003.There were 24 males and 21 females,ranging in age from 34 to 45 years old.The clinical data of the patients were analysed retrospectively.Result:All the patients were followed up for a period of 1 to 4 years after operation.22 cases(48.9%)were cured,18 cases(40%)were improved,but the other 5 cases(11.1%)were no effective.No serious complications and tumor recurrence occurred.Conclusion:The incidence of sinusitis in patients with NPC after radiotherapy is very high which interferes the effect of radiotherapy on NPC.Endoscopic sinus surgery is an effective method to open sinus ostium.It is feasible and favorable.