临产孕妇血清与新生儿脐血血清微量元素的研究

目的:探讨临产孕妇血清与新生儿脐血血清中微量元素钙、镁、锌、铁、铜的含量及其临床意义。方法:采用日立7 600型自动生化分析仪及罗氏自动生化分析仪测定210例孕妇血清及新生儿脐血血清的钙、镁、锌、铁、铜含量,并进行对照研究。结果:新生儿脐血血清中铁、钙、锌含量高于孕妇血清(P0.05);临产孕妇血清铜含量高于新生儿脐血血清(P0.05);新生儿脐血血清与临产孕妇血清中镁的含量比较无统计学差异(P0.05);维吾尔族孕妇血清及新生儿脐血血清与汉族孕妇血清及新生儿脐血血清钙、镁、铜、锌、铁含量无统计学差异(P0.05)。结论:①血清微量元素铁、钙、锌、镁的减少,铜的升高可能导致妊娠期疾病的发生。②无论孕妇机体在正常状态下还是在病理状态下,均需首先保证胎儿对锌、铜、铁、钙、镁的需要。③孕期应定期监测微量元素,合理补充微量元素钙、锌、铁,从而减少妊娠期疾病的患病率,保证孕妇身体健康和胎儿的正常生长发育。

Study on trace elements in serum of pregnant women in labor and umbilical cord serum of neonates

Objective:To explore the contents of calcium,magnesium,zinc,iron and copper in serum of pregnant women in labor and umbilical cord serum of neonates and their clinical significances.Methods:Hitachi 7600 automatic biochemical analyzer and Roche automatic biochemical analyzer were used to detect the contents of calcium,magnesium,zinc,iron and copper in serum of pregnant women in labor and umbilical cord serum of neonates,a comparative study was conducted.Results:The contents of iron,calcium and zinc in umbilical cord serum of neonates were significantly higher than those in serum of pregnant women in labor(P<0.05);the content of copper in serum of pregnant women in labor was significantly higher than that in umbilical cord serum of neonates(P<0.05);there was no difference in content of magnesium between umbilical cord serum of neonates and serum of pregnant women in labor(P>0.05);there was no difference in contents of calcium,magnesium,copper,zinc and iron in serum of pregnant women in labor and umbilical cord serum of neonates between Uygur nationality and Han nationality(P>0.05).Conclusion:The decreases of serum iron,calcium,zinc and magnesium contents and the increase of serum copper may lead to the occurrence of gestational diseases;whether pregnant women in normal state or in pathological state,ensuring the demands of fetuses for zinc,copper,iron,calcium and magnesium is very important;monitoring trace elements regularly during pregnancy and reasonable supplementation of calcium,zinc and iron may reduce the prevalence of gestational diseases and ensure physical health of pregnant women and normal growth and development of fetuses.