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| 妊娠合并甲状腺功能减退症对孕妇及胎儿的影响 | |
| 引用本文： | 赵艳晖,吴富菊,张炜旸,张为远,赵艳华.妊娠合并甲状腺功能减退症对孕妇及胎儿的影响[J].中国妇幼保健,2009,24(35):4982-4984. |
| 作者姓名： | 赵艳晖 吴富菊 张炜旸 张为远 赵艳华 |
| 作者单位： | 1. 吉林大学第二附属医院妇产科,吉林,长春,130041 2. 北京妇产科医院 3. 长春市中心医院 |
| 摘 要： | 目的:探讨妊娠合并甲状腺功能减退症对妊娠结局及胎儿的影响。方法:回顾性分析40例妊娠合并甲状腺功能减退症的患者资料,采用放免法测定其血清促甲状腺激素(TSH)、游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)浓度及其对妊娠结局和胎儿的影响。结果:妊娠合并甲状腺功能减退症孕妇的流产率、早产率、并发症发生率及新生儿TSH升高明显高于对照组(P<0.05),新生儿出生后1minApgar评分低于正常对照组(P<0.05)。结论:对妊娠合并甲状腺功能减退症的孕妇应定期监测血清FT3、FT4、TSH浓度,及时调整用药剂量,并密切关注各类并发症的出现,以减少不良妊娠结局的发生;对其新生儿建议取脐带血监测血清FT3、FT4、TSH浓度,以及时发现新生儿甲状腺功能减退症,并及时治疗。 |
| 关 键 词： | 甲状腺功能减退症 妊娠结局 新生儿 |
Effects of hypothyroidism during pregnancy on pregnant women and fetus |
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| Abstract: | Objective:To explore the effects of hypothyroidism during pregnancy on pregnant women and fetus.Methods:Clinical data of 40 pregnant women with hypothyroidism were analysed retrospectively,then serum levels of thyroid-stimulating hormone (TSH),free triiodothyronine (FT3) and free thyroxine (FT4) were detected by radioimmunoassay.Results:The incidences of abortion,premature delivery and complications of pregnant women and TSH level of neonatal infants in hypothyroidism group were significantly higher than those in control group (P<0.05).The 1 minute Apgar score of neonatal infants in hypothyroidism group was significantly higher than that in control group (P<0.05).Conclusion:The serum levels of FT3,FT4 and TSH in pregnant women with hypothyroidism should be monitored throughout gestation,so as to find hypothyroidism of neonatal infants early and offer timely treatment. |
| Keywords: | Hypothyroidism Pregnancy outcome Neonatal infants |
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