Prognostic factors in allogeneic transplantation for patients with high-risk multiple myeloma after reduced intensity conditioning |
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| Authors: | Lee Choon Kee Badros Ashraf Barlogie Bart Morris Christopher Zangari Maurizio Fassas Athanasios van Rhee Frits Cottler-Fox Michele Jacobson Joth Thertulien Raymond Muwalla Firas Mazher Syed Anaissie Elias Tricot Guido |
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| Institution: | The Myeloma Institute for Research and Therapy, The University of Arkansas for Medical Sciences, Little Rock, AR, USA. leehoonkee@uams.edu |
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| Abstract: | OBJECTIVES: The aim of this study was to identify prognostic factors for outcome of high-risk patients with multiple myeloma after allogeneic transplantation prepared by reduced intensity conditioning (RIC). MATERIALS AND METHODS: Data from 45 consecutive patients (median age 52 years, range 38-68), who received grafts from a sibling (n = 34) or unrelated donor (n = 11) were analyzed. Fourteen patients received an RIC allotransplant while chemosensitive (>/=partial remission PR]), whereas 31 chemoresistant patients (
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