Monoamine oxidase activity of macrophages at rest and during phagocytosis |
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| Authors: | I Fabian M Aronson |
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| Institution: | Department of Cell Biology and Histology, Sackler School of Medicine, Tel-Aviv University, Ramat Aviv, Israel |
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| Abstract: | Mouse macrophages contain monoamine oxidase (MAO) A activity and traces of MAO B, as judged by a strong deamination of 5-hydroxytryptamine and tyramine and a marginal one of benzylamine. Significant inhibition of MAO activity occurred in the presence of the specific inhibitors clorgyline and deprenyl. MAO A activity was considerably depressed in phagocytizing cells. |
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