Randomized, double-blind, placebo-controlled study to evaluate the effect of two dosing regimens of darbepoetin alfa in patients with heart failure and anaemia. |
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| Authors: | Dirk J van Veldhuisen Kenneth Dickstein Alain Cohen-Solal Dirk J A Lok Scott M Wasserman Nigel Baker Dylan Rosser John G F Cleland Piotr Ponikowski |
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| Institution: | Department of Cardiology, University Medical Center Groningen, University of Groningen, The Netherlands. d.j.van.veldhuisen@thorax.umcg.nl |
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| Abstract: | AIMS: Anaemia is common in chronic heart failure (CHF) and associated with worse outcome. This randomized, double-blind, placebo-controlled study evaluated the effect of two darbepoetin alfa dosing regimens on haemoglobin (Hb) rate of rise and clinical effects in patients with CHF and anaemia. METHODS AND RESULTS: Patients with CHF (>or=3 months), left ventricular ejection fraction (LVEF)
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