慢性阻塞性肺疾病稳定期患者胸部定量CT变化分析

目的探讨慢性阻塞性肺疾病稳定期患者胸部定量CT变化。方法统计分析2011年至2013年我院收治的100例慢性阻塞性肺疾病稳定期患者的临床资料。结果 VC、DLCO、FEF750、FEV1%pred在四组患者之间的差异均显著（P〈0.05）;CT为-1 024--970,-960,-950,-940,-930,-920,-910HU下LAA%结果均一致,四组患者的LAA%之间的差异均显著（P〈0.05）;CT为-1 024-910HU时LAA%、症状评分和DLCO、FEF750、F E V 1%p r e d均呈显著的负相关关系（P〈0.05）;LAA%和MMRC呈显著的正相关关系（P〈0.05）。结论胸部定量CT变化可以作为评估慢性阻塞性肺疾病稳定期患者病情严重程度的重要指标。

Chest CT Quantitative Change Analysis of Chronic Obstructive Pulmonary Disease Patients during Stabilization Period

Objective To investigate the chest CT quantitative change of chronic obstructive pulmonary disease patients during stabilization period. Methods The clinical data 100 cases of chronic obstructive pulmonary disease patients during stabilization period in our hospital from 2011 to 2013 were statistically analyzed. Results Results The differences of VC, DLCO, FEF750, FEV1% pred between the four groups were significant（P〈0.05）; LAA% under results CT for 1024-a 970, a 960, a 950, a 940, a 930, a 920, a 910 HU were consistent, the differences were significant（P〈0.05）; LAA%, symptom score and DLCO, FEF750, FEV1% pred showed significant negative correlation（P〈0.05）; LAA% and MMRC showed significant positive correlation under CT for 1 024-910HU（P〈0.05）. Conclusion Conclusion chest CT quantitative changes can be assessed as an important severity indicator of chronic obstructive pulmonary disease patients during stabilization period.