| ~1H磁共振波谱在颅脑转移瘤中的应用 |
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| 引用本文： | 董海波,戴嘉中,蔡佩武,沈天真,董亚非.~1H磁共振波谱在颅脑转移瘤中的应用[J].中国医学影像技术,2001,17(3). |
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| 作者姓名： | 董海波 戴嘉中 蔡佩武 沈天真 董亚非 |
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| 作者单位： | 1. 复旦大学医学院附属华山医院放射科,
2. 脑外科 |
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| 摘 要： | 目的 结合MRI探讨1H磁共振波谱 ( 1HMRS)在颅脑转移瘤中的应用价值。方法 选择 32例经临床确诊为颅脑转移瘤的患者 ,进行MRI及1HMRS检查。每例均行肿瘤区与健侧相应部位对照研究。结果 32例1HMRS均表现为明显增高的胆碱 (Cho)峰 ,肌酸 (Cr)峰下降甚至消失 ,无氮乙酰门冬氨酸 (NAA)峰 ,Cho /Cr比值升高。 11例出现乳酸 (Lac)峰 ,15例出现脂质 (Lipid)峰。结论 1HMRS可作为诊断本病的重要补充
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| 关 键 词： | 颅脑转移瘤 1H磁共振波谱 代谢 |
~1 H Magnetic Resonance Spectroscopy in the Diagnosis of Brain Metastasis |
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| DONG Hai bo,DAI Jia zhong,CAI Pei wu,et al.~1 H Magnetic Resonance Spectroscopy in the Diagnosis of Brain Metastasis[J].Chinese Journal of Medical Imaging Technology,2001,17(3). |
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| Authors: | DONG Hai bo DAI Jia zhong CAI Pei wu |
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| Abstract: | Purpose To evaluate 1 H magnetic resonance spectroscopy ( 1 H MRS)in the diagnosis of metastatic brain tumors with magnetic resonance imaging(MRI). Methods 32 cases diagnosed as brain metastases clinically had MRI and 1 H MRS examination . Each case had single voxel MR spectroscopy simultaneously both in the lesion's region and the contralateral side. Results 32 cases of 1 H MRS exhibited specific spectral peaks including prominent choline containing compounds (Cho), decreased or absent total creatine (Cr), absent acetylaspartate(NAA) the metabolic ratio showed significantly increased Cho/Cr; 11cases showed abnormal lactate (Lac). 15 cases exhibited abnormal Lipid. Conclusion 1 H MRS can improve diagnostic accuracy of brain metastasis. |
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| Keywords: | Brain metastasis 1 H MR spectroscopy Metabolite |
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