经静脉心肌声学造影无创性评价冠状动脉旁路 移植术疗效的临床研究

目的 探讨利声显经静脉心肌声学造影（IMCE）在冠状动脉旁路移植术（CABG）疗效评价中的价值。方法 对12例患者于CABG前后行IMCE检查，分析利声显输注和递增触发时的心肌多普勒信号并描绘时间一强度曲线，测量平台期心肌层显影强度A，曲线上升平均斜率β以及A，β乘积的治疗前后的变化。结果 所有患者均成功行CABG术及IMCE检查，CABG术后A，β及A，β值均显著增加（P＜0．001），结论 IMCF为无创性评价CABG的疗效提供了简便，安全和可靠的新途径。

Noninvasive Assessment of Coronary Artery Bypass Grafting by Intravenous Myocardial Contrast Echocardiography

Objective　To study the reliability of intravenous myocardial contrast echocardiography (IMCE) in assessing therapeutic effect of coronary artery bypass grafting (CABG) using intravenously infused Levovist. Methods　IMCE was performed in 12 patients before and after CABG. The power Doppler signals of the myocardial segments were analyzed and the time-amplitude curves were plotted during Levovist infusion and incremental triggering. The maximal amplitude score (A), the mean ascending slope of the curve (β) and the product of A*β were measured. Results　There was a significant increase in A, β and A*β after CABG (P<0.001).Conclusion　IMCE offers a simple and reliable approach to the noninvasive assessment of therapeutic effect of CABG.