左旋卡尼汀对冠心病并糖尿病患者的临床疗效观察 |
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引用本文: | 遇波,程向荣,石穆穆.左旋卡尼汀对冠心病并糖尿病患者的临床疗效观察[J].中外医疗,2009,28(29):88-89. |
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作者姓名: | 遇波 程向荣 石穆穆 |
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作者单位: | 1. 哈尔滨医科大学第五附属医院高干病房,黑龙江大庆,163000 2. 黑龙江省鸡西市矿业集团总医院,黑龙江鸡西,158100 3. 哈尔滨医科大学大庆校区,黑龙江大庆,163319 |
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摘 要: | 目的观察左旋卡尼汀对冠心病并糖尿病患者临床疗效。方法60例冠心病并糖尿病患者随机分为常规治疗组(对照组,30例)和左旋卡尼汀组(治疗组,30例),对照组给予抗血小板、钙离子阻滞剂、β受体阻滞剂及硝酸脂类药物等常规治疗治疗,治疗组在此基础上加用国产左旋卡尼汀5g静脉滴注,1次/d,连续用药21d。观察治疗前及治疗后患者的心绞痛发生次数、硝酸甘油片用量及血糖血脂的变化。结果与治疗前相比,治疗组的心绞痛发生次数、硝酸甘油片用量明显改善,同时血糖明显下降。结论左旋卡尼汀可以辅助治疗冠心病并糖尿病患者,减轻心肌缺血及临床症状,同时可降低血糖。
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关 键 词: | 左卡尼汀 冠心病 糖尿病 |
Clinical Investigation of L-Carnitine on the Patients with Coronary Heart Disease and Type-II Diabetes |
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Institution: | YU Bo CHENG Xiangrong SHI Mumu |
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Abstract: | Objective To evaluate the effects of L-carnitine on the with coronary heart disease and type-Ⅱ diabetes.Methods Sixty patients with coronary heart disease and type-Ⅱ diabetes were divided into conventional therapy group(control group,30patients) and L-carnitine therapy group(therapy group,30 patients).The control group patients were given basic treatment;the therapy group were given L-carnitine 5gPd for 21 days in addition to the basic treatment.Angina pectoris attack frequency,weekly nitroglycerin consumption and glucose&lipid in heart failure patients was observed before and after L--carnitine treatment. Results After treatment, angina pectoris attack frequency,weekly nitroglycerin consumption of patients increased significantly in L-carnitine group, accompanied by decrease in blood glucose level. Conclusion L--carnitine can be used as adjuvant therapy to improve the patients with coronary heart disease and type--Ⅱ diabetes. |
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Keywords: | L-carnitine Coronary heart disease Type-Ⅱ diabetes |
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