北京地区孕前及孕早期妇女TORCH感染情况调查

目的通过化学发光免疫分析法测定北京地区育龄妇女血清中TORCH抗体,对其感染的阳性率进行调查,为本区域孕妇保健提供参考依据。方法调查对象为在我院进行孕前筛查和孕12周前普查的妇女,共计5 870名,TORCH抗体的测定采用化学发光免疫分析法（CLIA）。结果TORCH-IgM抗体总阳性率达19.3%,其中以单纯疱疹病毒（Ⅰ＋Ⅱ）感染阳性率最高,为10.5%。调查发现秋冬季节为弓形虫、风疹病毒感染的相对高发期,巨细胞病毒（CMV）感染在夏秋季节发病率较高。IgG类抗体中CMV IgG的阳性率最高,达92.4%。结论北京地区孕前和孕早期妇女TORCH感染率较高,积极的进行监测以预防先天性TORCH感染是非常必要的。

Investigation of TORCH infection among women before pregnancy or in the early period of pregnancy in Beijing

Objective To investigate the infective rate of toxplasma（ TOX）, rubellavirus （RV）, cytomegalovirus （CMV） and herpes simplex virus （HSV） antibody （anti-TORCH） among women by chemiluminescence immunoassay （CLIA） at childbearing age and offer the reference for health care among pregnant women. Methods A total of 5 870 women before pregnancy or in the early period of pregnancy were collected in this study. Anti-TORCH was detected by CLIA. Results The total positive rate of TORCH-IgM was 19.3%, with the highest positive rate of HSV（ Ⅰ ＋ Ⅱ ） IgM （ 10.5% ）. The results showed that the positive rates of anti-TOX IgM and anti-RV IgM were higher during autumn and winter, and the infective rate of CMV was higher during summer and autumn. In TORCH-IgG, CMV IgG had the highest infective rate, 92.4%. Conclusions The infective rate of TORCH is pretty high among women before pregnancy or in the early period of pregnancy in Beijing. Entirely new approaches to monitoring and prevention of congenital TORCH infection are necessary.