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菲立磁增强MR不同序列对肝脏病变的对比研究
引用本文:孟祥水,高俊玲,丛培新,张红蕾,王茜,郑金勇,王洪波,李传福.菲立磁增强MR不同序列对肝脏病变的对比研究[J].山东大学学报(医学版),2002,40(6):559-560.
作者姓名:孟祥水  高俊玲  丛培新  张红蕾  王茜  郑金勇  王洪波  李传福
作者单位:1. 山东大学齐鲁医院放射科
2. 烟台市毓璜顶医院
摘    要:目的:探讨菲立磁在肝脏占位性病变诊断中的应用价值。方法:对17例肝脏占位性病变的患者,行MR平扫和菲立磁增强MRI检查,扫描序列为T2W/TSE、T1W/SE、T2FS/TSE和T2W/FFE、T1W/FFE,比较增强前后肝脏的信噪比(SNRN)和病灶信噪比(SNRM)及发现病灶的数量、形态。结果:菲立磁增强后五个序列的肝脏信号强度均较平扫明显下降(P<0.01),T2W/TSE、T2FS/TSE、T2W/FFE肝脏信号强度下降程度较为显著;但病变的信号强度变化不大(P>0.05)。结论:菲立磁增强T2W/TSE,T2FS/TSE、T2W/FFE可明显提高肝脏占位性病变的检出率,T1W/SE和T1W/FFE在肝脏局灶性病变的定性诊断中具有潜在价值。

关 键 词:肝脏  磁共振成像  超顺磁性氧化铁
文章编号:1671-7554(2002)06-0559-02
修稿时间:2002年6月10日

Comparison between Different Sequences of Feridex-enhanced and rutine MRI for the Detection of focal Hepatic lesions
MENG Xiang-shui,GAO Jun-ling,CONG Pei-xin,et al.Comparison between Different Sequences of Feridex-enhanced and rutine MRI for the Detection of focal Hepatic lesions[J].Journal of Shandong University:Health Sciences,2002,40(6):559-560.
Authors:MENG Xiang-shui  GAO Jun-ling  CONG Pei-xin  
Abstract:Objective:To evaluate Feridex(superparamagnetic iron oxide,SPIO)enhanced MRI in the diagnosis of focal hepatic lesions.Methods:Routine and Feridex-enhanced MRI were performed in17patients with suspected focal hepatic lesions.The pulse sequences of Feridex included:T 2 W/TSE,T 1 W/SE,T 2 FS /TSE,T 2 W/FFE,T 1 W/FFE.The effects of Feridex on signal intensity,SNR m of lesion vs normal hepatic tissue were assessed with quantitative analysis.Results:Compared with routine scanning,the signal intensity of liver on Feridex-enhanced MRI was significantly decreased while the signal intensity of lesions showed no marked changes.Conclusion:The detection of focal hepatic lesions can be significantly im-proved with Feridex-enhanced T 2 W/TSE,T 2 FS /TSE,T 2 W/FFE,which has potential values for qualitative diagnosis of such lesions.
Keywords:Superparamagnetic iron oxide  Liver  Magnepic Resonance Imaging
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