Alpha-fetoprotein and phagocytosis in athymic nude mice |
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| Authors: | V V?tvicka M Holub H Kovár? P Siman F Kovár? |
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| Affiliation: | Institute of Microbiology, Czechoslovak Academy of Science, Prague. |
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| Abstract: | Alpha-fetoprotein (AFP) was found to suppress the phagocytic activity of the blood monocytes and neutrophils in vitro. The amounts of AFP detectable by immunofluorescence in the livers of nu/nu, nu/+ and +/+ mice were quite comparable, and thus could not have been responsible for the alterations in phagocytosis found in leukocytes of athymic nude mice during their ontogenetic development. |
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