乳腺隐匿性病灶的微创活检

目的:探讨X线立体定位下核芯针穿刺活检(SCNB)对乳腺隐匿性病灶(NPBL)的临床应用价值。方法:运用乳腺X线立体定位系统对59例NPBL进行SCNB,其中42例行手术切除,将活检标本病理结果与X线表现、手术标本病理结果进行对照。结果:59例SCNB结果中良性病变43例,恶性病变16例(导管原位癌5例、浸润性导管癌11例),其中26例良性病变及16例恶性病变共42例行手术治疗,术后病理结果为良性病变25例,恶性病变17例(导管原位癌5 例、浸润性导管癌11例、硬癌1例)。与手术病理结果对照,SCNB对NPBL的诊断敏感度为94％,特异度为100％。结论:SCNB是诊断NPBL简便、实用、微创的方法,可获得准确的组织病理学结果,提高早期乳腺癌的检出率及降低良性病变的手术活检率。

Minimal Invasive Biopsy for Nonpalpable Breast Lesions

Objective:To discuss the clinical value of the application of stereotatic core needle biopsy (SCNB) to non-palpable breast lesion (NPBL). Methods: 59 cases of NPBL were biopsied under the guidance of computed stereotatic localized equipment. Among them,surgery were performed in 42 cases. Correlation of the X-ray findings,pathologic diagnosis of SCNB with the final pathology diagnosis were done. Results: Pathologic diagnosis of biopsy specimen of 59 cases were as follows: benign lesions (n = 43) , malignant lesions (n=16 , including five cases with ductal carcinomas in situ and eleven cases with invasive ductal carcinomas). Benign lesions (n=25) or malignant lesions (n=16) proved by SCNB underwent surgical procedures which resulted in the following findings:benign lesions in 25 cases,malignant lesions in 17 cases including ductal carcinomas in situ (n=5),invasive ductal carcinomas (n=11) and scirrhus (n=l). The sensitivity and specificity of SCNB according to the results from surgical procedures were 94% and 100% respectively. Conclusion:SCNB is a convenient and practical diagnostic method with minute trauma. The detection rate of early stage of breast cancer can be improved and the rate of operation for benign lesions can be decreased.