| 基于体素的形态学分析技术在评价脑灰质体积改变对皮质下缺血性血管性痴呆患者执行功能影响中的应用 |
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| 引用本文： | 邹坤霞,杨骏,张庆萍,袁爱红,李传富,徐春生,雍启正. 基于体素的形态学分析技术在评价脑灰质体积改变对皮质下缺血性血管性痴呆患者执行功能影响中的应用[J]. 中国中西医结合影像学杂志, 2021, 0(1): 37-42,46 |
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| 作者姓名： | 邹坤霞 杨骏 张庆萍 袁爱红 李传富 徐春生 雍启正 |
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| 作者单位： | 1.安徽中医药大学第一附属医院 针灸康复二科，安徽 合肥 230031;2.安徽中医药大学第一附属医院 影像科，安徽 合肥 230031;3.安徽中医药大学，安徽 合肥 230000;4.安徽中医药大学第三附属医院针灸康复一科，安徽 合肥 230000 |
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| 基金项目： | 国家自然科学基金项目(8157151194,8187151181);安徽省科技攻关计划项目(1804h08020255);杨骏全国名老中医药专家传承工作室。 |
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| 摘 要： | 目的:采用基于体素的形态学分析(VBM)技术分析皮质下缺血性血管性痴呆(SIVD)患者执行功能障碍与相关脑区灰质体积改变之间的关系.方法:分别纳入SIVD患者和健康志愿者各14例,应用VBM技术比较2组的脑灰质体积差异,分析脑灰质体积变化与执行功能的相关性.结果:与健康对照组相比,SIVD患者灰质体积显著减少,包括全脑...
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| 关 键 词： | 磁共振成像 大脑皮质 痴呆,血管性 执行功能 |
Analysis of the effect of brain gray matter volume change on executive function of subcortical ischemic vascular dementia patients based on VBM technology |
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| ZOU Kunxia,YANG Jun,ZHANG Qingping,YUAN Aihong,LI Chuanfu,XU Chunsheng,YONG Qizheng. Analysis of the effect of brain gray matter volume change on executive function of subcortical ischemic vascular dementia patients based on VBM technology[J]. Chinese Imaging Journal of Integrated Traditional and Western Medicine, 2021, 0(1): 37-42,46 |
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| Authors: | ZOU Kunxia YANG Jun ZHANG Qingping YUAN Aihong LI Chuanfu XU Chunsheng YONG Qizheng |
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| Affiliation: | (Second Department of Acupuncture Rehabilitation,the No.1 Affiliated Hospital of Anhui University of TCM,Hefei 230031,China) |
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| Abstract: | Objective:Using voxel-based morphometry(VBM)technology to analyze the relationship between executive function of subcortical ischemic vascular dementia(SIVD)patients and changes of gray matter volume in related brain regions.Methods:This study included 14 cases of SIVD patients and 14 healthy persons respectively.The VBM technology analysis method was used to compare the difference in gray matter volume between the two groups,and the correlation between brain gray matter volume change and executive function was analyzed.Results:Compared with the healthy control group,the gray matter volume of SIVD patients was significantly reduced,including the frontal lobe,temporal lobe,anterior cingulate gyrus,orbitofrontal lobe,occipital lobe,fusiform gyrus,anterior cuneiform lobe,hippocampus,thalamus and right cerebellum.SIVD patients had not been found a brain area with increased gray matter volume.Conclusion:Patients with SIVD have atrophy of brain gray matter volume,especially middle frontal gyrus,which is related to the degree of executive function impairment. |
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| Keywords: | Magnetic resonance imaging Cerebral cortex Dementia,vascular Executive function |
| 本文献已被 CNKI 维普 等数据库收录！ |
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