FC患儿发病年龄、发作次数及脑电图与预后的关系

目的 探讨热性惊厥(FC)患儿的发作年龄、发作次数与预后的关系.方法 对146例FC患儿的发病年龄、发作次数、24h动态脑电图和3年随访结果进行回顾性分析.结果 在 146例FC患儿中,总异常率为30.1%,在异常脑电图中,非特异性异常22.6%,特异性异常7.5%;分组比较,性别之间差异无显著性(X2=2.33,P>0.05);≥3岁组和<3岁组AEEG总异常率分别为14.7%和46.5%,差异有显著性(X2=-18.29,P<0.01);反复发作组明显高于首发组(x 2=-23.87,P<0.01)、有家族史组明显高于无家族史组(X2=-10.18,P<0.01).非特异性异常组脑电图组的患儿1-3年随访痊愈率分别51.7%(15/29)、69.O%(20/29)和82.8%(24/29);特异性异常组分别为10.0%(1/10)、20.0%(2/10)和40.0%(4/10).非特异性异常的患儿其预后明显优于特异性异常的患儿,两者比较差异有显著性(P<0.05).结论 FC患儿的预后与发病年龄、发作次数和家族史有密切关系.

Relationships between prognosis and age of onset, seizure frequency and EEG in children with febrile convulsion

[Objective] To explore the relationship between prognosis and age of onset, seizure frequency and EEG in children with febrile convulsion. [Methods] Retrospective analyses were made on age of onset, seizure frequency, 24h-AEEG and 3 year follow-up outcomes in 146 children with febrile convulsion. [Results] Among the 146 children, total abnormal rate was 30.1%, non-specific and specific abnormalities of abnormal EEG were respectively 22.6% and 7.5%. There was no significant difference in gender (P >0.05). Th...