胰腺神经内分泌肿瘤诊疗现状

神经内分泌肿瘤（NEN）是一种罕见的高异质性肿瘤，起源于肽能神经元和神经内分泌细胞，可发生在支气管、肺部和胃肠、胰腺等多种部位，我国以胰腺神经内分泌肿瘤（pNEN）最为多见，近几十年来发病率显著上升。笔者主要从pNEN的分级标准、诊断、治疗等方面对该疾病的最新诊疗研究现状进行介绍，以期为临床诊疗提供指导和参考。

Current status of diagnosis and treatment of pancreatic neuroendocrine neoplasms

Neuroendocrine neoplasms (NENs) are rare and highly heterogeneous tumors originating from peptidergic neurons and neuroendocrine cells. They can occur in various sites such as bronchopulmonary and gastroenteropancreatic systems. Pancreatic neuroendocrine neoplasms (pNENs) are the most common in our country, with a significant increase in incidence in recent decades. Here, the authors primarily discusse the latest research status on the classification, diagnosis, and treatment of pNENs, aiming to provide guidance and reference for clinical diagnosis and treatment.