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Pseudotumoral Presentation of Cerebral Amyloid-Beta Angiopathy: Case Report and Review of Literature |
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| Authors: | Claudia Uribe Roca Fabio Maximiliano Gonzalez Marta Ines Bala Miguel Saucedo Lucrecia Bandeo Luciana Leon Cejas Sol Pacha Pablo Bonardo Carlos Rugilo Pablo Dezanzo Rafael Torino Gustavo Sevlever Manuel Fernandez Pardal Ricardo Reisin |
| Affiliation: | 1.Department of Neurology, Buenos Aires British Hospital, Buenos Aires, Argentina; 2.Department of Neuroradiology, Buenos Aires British Hospital, Buenos Aires, Argentina; 3.Department of Pathology, Buenos Aires British Hospital, Buenos Aires, Argentina; 4.Department of Neurosurgery, Buenos Aires British Hospital, Buenos Aires, Argentina; 5.Department of Pathology, FLENI, Buenos Aires, Argentina |
| Abstract: | ObjectiveCerebral amyloid angiopathy-related inflammation (CAA-RI) is a rare and potentially treatable encephalopathy that usually affects people older than 50 years old and has an acute or subacute clinical presentation characterized by rapidly evolving cognitive decline, focal deficits and seizures. In a small subset of patients the disease can adopt a pseudotumoral form in the neuroimages that represents a very difficult diagnostic challenge. MethodsHere in we report a patient with a tumour-like presentation of histopathologically confirmed CAA-RI. ResultsWe also conducted a search and reviewed the clinical and radiological features of 41 cases of pseudotumoral CAA-RI previously reported in the literature in order to identify those characteristics that should raise diagnostic suspicions of the disease, there by avoiding unnecessary surgical treatments. ConclusionThe therapy of CAA-RI with steroids is usually effective and clinical and radiological remission can be achieved in the first month in approximately 70% of cases. |
| Keywords: | Cerebral amyloid angiopathy Pseudotumoral Tumor-like Neoplasm |