儿童交替性偏瘫六例分析

目的探讨儿童交替性偏瘫（ＡＨＣ）的临床特点及治疗方法。方法对６例ＡＨＣ患儿的临床资料进行分析。结果６例患儿的临床特征为出生后１８个月起内病，频繁发作，持续数分钟至数小时；短暂的眼球震颤，肌张力异常，舞蹈徐动样动作，植物神经机能紊乱和认知机能减退；睡眠可缓解无力及锥体外系症状。应用氟桂嗪治疗后，１例患儿发作完全停止，其余５例患儿均显示发作频率和持续时间降低。结论本病的主要特征为１８个月内起病的发作性交替性偏瘫，伴锥体外系症状及智力障碍，氟桂嗪治疗本病有效

Alternating hemiplegia of childhood

Objective To explore the clinical features and treatment of alternating hemiplegia of childhood (AHC). Methods Six children with AHC were studied prospectively. Results They were characterized by onset before 18 monthes of age, frequent episodes of alternating paralysis lasting from a few minutes to several hours, together with transient occular palsies, nystagmus, choreoathetosis, autonomic dysfunction and development of congnitive impairment. Sleep consistently relieved both weakness and associated symptoms of extrapymidal system. The six children were treated with flunarizine, one of them had completely ceased episodes, and others showed a reducted frequency and duration of the hemiplegic attacks.Conclusion Alternating hemiplegia occurred before 18 monthes of age, and complicated paroxysmal phenomena and cognitive impairment, flunarizine may be an effective agent in treating AHC.