HLA antigens in ulcerative colitis: a study in the Sicilian population |
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| Authors: | Calogero Caruso Patrizia Palmeri Lorenzo Oliva Ambrogio Orlando Mario Cottone |
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| Affiliation: | Servizio di Immunologia Tissutale, Istituto di Patologia generale dell'Universitàdi Palermo;Cattedra di Clinica Medica R dell'Universitàdi Palermo, Ospedale V. Cervello, Palermo, Italy |
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| Abstract: | HLA antigens were investigated in 41 Sicilian patients with ulcerative colitis and in 151 healthy controls. Frequencies of HLA-B5 and DR2 were increased in the group of patients with ulcerative colitis whereas the DR3 antigen frequency was decreased. However the corrected p values were not significant. Thus, present results indicate that in ulcerative colitis HLA linked genetic factors play a marginal role, if any. |
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