中药联合光疗治疗寻常型银屑病的临床疗效观察

比较单纯中药和中药结合低强度窄波中波紫外光(low intensity narrow-band ultraviolet B, LUVB)和低强度810 nm半导体激光(low intensity 810 nm diode laser irradiation, LIL)对寻常型银屑病的临床疗效。从2007年3月至2010年3月的三年间,将186例寻常型银屑病患者随机分为治疗组96例和对照组90例,分别采用中药结合LUVB与LIL和单纯中药治疗3个月。治疗组痊愈39例(40.63 %),显效42例(43.75 %),有效4例(13.54 %),无效2例(2.09 %),总有效率达到了97.91 %。对照组痊愈18例(20.00 %),显效20例(22.22 %),有效23例(25.56 %),无效29例(32.22 %),总有效率达到了67.8 %。结果表明,中药联合LUVB和LIL这种新的治疗方案对寻常型银屑病的治疗优于单纯中药治疗,具有相对疗程短,疗效确切,治愈率高,复发率低,安全性好等特点,适宜基层医院推广应用。

Clinical Therapeutic Effect Observation of Treating Psoriasis Vulgaris with Traditional Chinese Medicine and Phototherapy

Objective: To compare the clinical therapeutic effects of the simple traditional Chinese medicine (TCM) only and the TCM in combination with low intensity narrow-band ultraviolet B (LUVB) and low intensity 810nm diode laser irradiation (LIL) in the treatment of psoriasis vulgaris. Methods: A total of 186 patients with psoriasis vulgaris treated between March of 2007and March of 2010 were randomly divided into a treatment group (96 patients) and a control group (90 patients) to respectively receive the treatment of TCM in combination with LUVB and LIL and the treatment of TCM only for three months, and the therapeutic effects of the two treatments were observed and compared. Results: In the treatment group, 39 patients were cured (40.63 %), 42 patients showed very effective (43.75 %), 13 showed effective (13.54 %) and 2 showed ineffective (2.09 %), with a total effective rate of 97.91 %, while in the control group, 18 were cured (20.00 %), 20 showed very effective (22.22 %), 23 showed effective (25.56 %) and 29 showed ineffective (32.22 %), with a total effective rate of 67.77 %. Conclusion: TCM in combination with LUVB and LIL is superior to the treatment of TCM only in treating psoriasis vulgaris in that it has such advantages as shorter treatment course, definite therapeutic efficacy, higher curative rate, lower relapse rate, higher safety and etc. Thus, it is suitable to be popularized and applied in community-level hospitals.