9+X法直肠超声引导下经会阴前列腺穿刺活检420例分析

目的:探讨9+X法经直肠超声引导下经会阴前列腺穿刺活检术诊断前列腺癌的临床价值及安全性。方法:回顾性分析2004年1月至2008年12月行9+X法经直肠超声引导下经会阴前列腺穿刺活检术的可疑前列腺癌患者420例临床资料。结果:穿刺确诊前列腺癌160例(阳性率38.1%)。PSA<4μg/L、4～10μg/L、>10μg/L、直肠指检(DRE)异常、经直肠或经腹部超声检查有异常者阳性率分别为7.4%、17.8%、65.4%、25.0%、22.2%。穿刺术后79例出现血尿(18.8%),急性尿潴留13例(3.1%),发热9例(2.1%),无其他严重并发症。结论:9+X法经直肠超声引导下经会阴前列腺穿刺阳性率高,并发症少,是诊断前列腺癌的理想方法。

TRUS-guided transperineal biopsy with 9+X method for the diagnosis of prostate carcinoma: Retrospective analysis of 420 cases

Objective:To explore the clinical value and safety of TRUS-guided transperineal biopsy with the 9+X method in the diagnosis of prostate carcinoma. Methods:A total of 420 men underwent TRUS-guided transperineal biopsy with the 9+X method for suspected prostate carcinoma. Their clinical data were retrospectively analyzed. Results:Prostate carcinoma was detected in 160 (38.1%) of the 420 cases,accounting for 7.4%,17.8% and 65.4% in those with PSA < 4.0 μg/L,4-10 μg/L and >10 μg/L respectively,25.0% in those with abnormal findings on digital rectal examination (DRE),and 22.2% in those with abnormal echoes on TRUS or abdominal ultrasound examination. Complications after prostatic biopsy included gross hematuria in 79 cases (18.8%),acute urinary retention in 13 (3.1%) and fever in 9 (2.1%),but no other serious complications were observed. Conclusion:TRUS-guided transperineal biopsy with the 9+X method,with high accuracy and fewer complications,is an ideal approach to the diagnosis of prostate carcinoma.