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甲状腺激素对血清脂类、脂蛋白胆固醇及~(125)I-LDL清除率的影响
引用本文:孙秀君,徐松德. 甲状腺激素对血清脂类、脂蛋白胆固醇及~(125)I-LDL清除率的影响[J]. 山东大学学报(医学版), 1991, 0(1)
作者姓名:孙秀君  徐松德
作者单位:山东医科大学生物化学教研室,山东医科大学生物化学教研室
摘    要:观察了不同甲状腺功能状态下血清脂类、脂蛋白水平及对LDL清除率的影响。甲状腺素组的T-C,(VLDL+LDL)-C,TG及(VLDL+LDL)-C/HDL-C降低,HDL-C升高,~(125)I-LDL清除率增加。他巴唑组的T-C,(VLDL+LDL)-C,HDL-C,TG,及(VLDL+LDL)-C/HDL-C均升高,~(125)I-LDL清除率有下降趋势。提示体内甲状腺激素水平的变化对血清脂类及脂蛋白胆固醇的代谢有明显影响

关 键 词:甲状腺激素  胆固醇  脂蛋白类  高密度  脂蛋白类  低密度  脂蛋白类  极低密度

THE EFFECT OF THYROID HORMONES ON SERUM LIPIDS LIPOPROTEINS AND ~(125)I-LDL CLEARANCE RATE
Sun Xiujun,Xu Songde Dept.of Biochemistry,Shandong Medical University. THE EFFECT OF THYROID HORMONES ON SERUM LIPIDS LIPOPROTEINS AND ~(125)I-LDL CLEARANCE RATE[J]. Journal of Shandong University:Health Sciences, 1991, 0(1)
Authors:Sun Xiujun  Xu Songde Dept.of Biochemistry  Shandong Medical University
Abstract:This article analysed the levels of serum lipids lipoproteins andLDL clearance rate on rabbits under different thyroid functions.45 male rab-bits(weight 2-3 kg)were divided into three groups(thyroid-fed group,tapazole-fed group and control group)at random,It was found that thyroid-fed group:the levels of T-C,(VLDL+LDL)-C,TG and(VLDL+LDL)-C/HDL-C were lowered,the levels of HDL-C rose,~(125)I-LDL clearance rateelevated;tapazole-fed group:the levels of T-C,(VLDL+LDL)-C,HDL-C,TG and(VLDL+LDL)-C/HDL-C were all raised.~(125)I-LDL clearance ratewas decreased,but no statistic difference.These results suggested that the changeof thyroid hormone levels in vivo possessed evident effects on metabolism ofserum lipids and lipoproteins.
Keywords:Thyroid hormones  Cholesterol  Lipoproteins  HDL  Lipoproteins  LDL  Lipoproteins  VLDL
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