抗肝纤维化的中药有效成分及其作用机制研究进展

肝纤维化是多数慢性肝病所共有的病理特征,肝纤维化逐步发展形成肝硬化,最终导致肝癌。本文将近年报道的具有抗HF作用的中药有效成分作简单综述,归纳为黄酮类、生物碱类、萜类、酚类化合物,并总结了各类有效成分抗HF的作用机制,为深入开展中药抗HF的研究提供一定的参考。

Advances in active ingredients and action mechanism of TCM in treatment of hepatic fibrosis

Hepatic fibrosis was the common feature of pathology in almost all patients with chronic liver injury, which led to cirrhosis gradually and liver cancer ultimately. The anti-hepatic fibrosis active ingredients from TCM, including flavones, alkaloids, terpenes and phenols compounds were reviewed with the action mechanism in this paper, which could provide some references for the further study about the anti-hepatic fibrosis of TCM.