| 康莱特增加肺癌细胞对健择敏感性的实验研究 |
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| 引用本文： | 李瑛,焦顺昌,戴广海,孙胜杰,魏秀芳. 康莱特增加肺癌细胞对健择敏感性的实验研究[J]. 现代肿瘤医学, 2007, 15(10): 1388-1390 |
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| 作者姓名： | 李瑛 焦顺昌 戴广海 孙胜杰 魏秀芳 |
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| 作者单位： | 解放军总医院肿瘤科,北京,1000853 |
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| 摘 要： | 目的:研究康莱特联合化疗药物健择抑制人肺腺癌细胞95D生长的作用,同时寻找康莱特联合化疗药物健择作用的最佳时机。方法:采用MTT比色法进行检测。结果:康莱特单药对人肺腺癌95D的生长有抑制作用,联合健择的抑制率高于单药组;康莱特先于健择加入对95D的抑制最强。结论:康莱特体外对肺癌细胞有抗肿瘤和化疗增敏作用;康莱特先于健择加入对95D的抑制最强。
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| 关 键 词： | 康莱特 肺癌细胞 化疗增敏 |
| 文章编号： | 1672-4992-(2007)10-1388-03 |
| 修稿时间： | 2007-03-09 |
Increasing sensitivity of KLT injection on lung cancer cell to Gemzar |
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| LI Ying,JIAO Shun-chang,DAI Guang-hai,SUN Sheng-jie,WEI Xiu-fang. Increasing sensitivity of KLT injection on lung cancer cell to Gemzar[J]. Journal of Modern Oncology, 2007, 15(10): 1388-1390 |
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| Authors: | LI Ying JIAO Shun-chang DAI Guang-hai SUN Sheng-jie WEI Xiu-fang |
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| Abstract: | Objective:To investigte the effects of KLT on drug sensitivity of Gemzar to 95D cells in vitro.Methods:MTT assay was used.Ruslts:Various concentration of KLT and Gemzar could inhibit the proliferation of 95D cells.KLT could increase the sensitivity of Gemzar to 95D cells(P<0.005).Especially when KLT was used before Gemzar.Conclusion:KLT could sensitize 95D cells to Gemzar in vitro. |
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| Keywords: | MTT |
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