| 阿奇霉素与氨苄西林-舒巴坦治疗下呼吸道感染的最小成本分析 |
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| 引用本文： | 董华.阿奇霉素与氨苄西林-舒巴坦治疗下呼吸道感染的最小成本分析[J].中国药房,2007,18(14):1050-1052. |
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| 作者姓名： | 董华 |
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| 作者单位： | 山东省枣庄市立医院,枣庄市,277102 |
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| 摘 要： | 目的:评价注射用阿奇霉素(AZM)与氨苄西林-舒巴坦(AMS)治疗下呼吸道感染的经济性。方法:将100例下呼吸道感染患者随机分为AZM组与AMS组,分别应用AZM、AMS治疗5～7d、7～14d,对2种用药方案进行最小成本分析。结果:AZM组、AMS组平均成本分别为1331·00、3167·39元,差异有统计学意义(P<0·01);总有效率分别为90·0%、84·0%(P>0·05),成本-效果比分别为1478·9、3770·7元。结论:AZM治疗方案较佳。
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| 关 键 词： | 阿奇霉素 氨苄西林-舒巴坦 最小成本分析 下呼吸道感染 |
| 文章编号： | 1001-0408(2007)14-1050-03 |
| 收稿时间： | 06 20 2006 12:00AM |
| 修稿时间： | 09 11 2006 12:00AM |
Azithromycin and Ampicillin-Sulbactam for Lower Respiratory Infection: Cost-minimization Analysis |
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| DONG Hua.Azithromycin and Ampicillin-Sulbactam for Lower Respiratory Infection: Cost-minimization Analysis[J].China Pharmacy,2007,18(14):1050-1052. |
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| Authors: | DONG Hua |
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| Institution: | Zaozhuang City Public Hospital in Shandong,Zaozhuang 277102,China |
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| Abstract: | OBJECTIVE:To evaluate the economic effects of azithromycin(AZM) and ampicillin/sulbactam(AMS) in trea-ting lower respiratory infection so as to optimize a treatment scheme with better curative effect but lower cost.METHODS:A total of 100 patients with lower respiratory infection were randomly assigned to receive AZM for 5～ 7 days or AMS for 7～ 14d,with cost-minimization analysis conducted on the 2 therapeutic schemes.RESULTS:The average cost for AZM vs.AMS scheme was 1 331.00 vs.3 167.39 yuan,showing significant differences(P<0.01) between 2 schemes.The total effective rate and the cost-effectiveness ratio of AZM vs.AMS scheme were 90.0% vs.84.0%(P>0.05) and 1 478.9 vs.3 770.7,respectively.CONCLUSION:The homemade azithromycin is preferable compared with AMS. |
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| Keywords: | Azithromycin Ampicillin/sulbactam Cost-minimization analysis Lower respiratory infection |
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