婴幼儿肺炎血清维生素A、维生素E含量研究

目的　测定婴幼儿肺炎血清维生素 A和维生素 E含量 ,探讨其状况与疾病相互关系 ,为临床防治提供参考。方法　采用反相高效液相色谱法 ,同时测定血清中维生素 A、维生素 E含量 ,对 5 0例婴幼儿肺炎住院患儿进行检测并与同期 5 0名体检健康婴幼儿对照。结果　婴幼儿肺炎组维生素 A均值明显低于健康组 (t=3.5 82 ,P<0 .0 0 1) ;亚临床维生素 A缺乏及可疑诊断的检出率明显高于健康对照组 (X2 =19.0 14,P<0 .0 0 1)。婴幼儿肺炎组维生素 E水平与对照组比较 ,差异不显著 (P>0 .0 5 )。结论　婴幼儿肺炎血清中维生素 A状况低于健康者 ,而亚临床缺乏的发生率高于健康婴幼儿。

Study on Vitamin A and Vitamin E in Infantile Pneuomonia

Objective：To study the levels of serum Vitamin A and Vitamin E in infantile pneumonia．Methods：In 50 cases with infantile pneumonia and 50 cases controls，Serum Vitamin A and Vitamin E level were simultaneously determined by RP-HLPC method．Results：The serum Vitamin A levels of the cases with infantile pneumonia and healthy infants were 0.935±0.433μmol／L and 1.211±0.356 μmol／L，respectively（t＝3.582，P＜0.001）．The incidences of preclinical Vitamin A deficiency，dubious diagnosis were 32％，38％ and 4％，28％ respectively （x2＝19.014，P＜0.001)and the levels of serum Vitamin E was not markedly changed as compared with the normal controls．Conclusions：It was suggested that the serum Vitamin A level of infants with pneumonia was clearly lower than that of the healthy infants and the incidence of preclinical Vitamin A deficiency was significantly higher than that of the healthy control group．