| 缬沙坦治疗原发性高血压患者左室肥厚的疗效观察 |
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| 引用本文： | 巩成翠,尹建华,孙庆荣.缬沙坦治疗原发性高血压患者左室肥厚的疗效观察[J].医学理论与实践,2006,19(9):1009-1010. |
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| 作者姓名： | 巩成翠 尹建华 孙庆荣 |
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| 作者单位： | 山东省滨州市中心医院,251700 |
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| 摘 要： | 目的:观察缬沙坦对原发性高血压(EH)患者的降压作用和对左室肥厚(LVH)的影响。方法:58例EH患者(其中有LVH者32例),口服缬沙坦80~160mg/d,共8个月。观察血压、不良反应,治疗前后测血脂、血糖及肝肾功能,并行超声心动图检查。结果:EH患者经缬沙坦治疗后收缩压、舒张压均有显著下降(P<0.01),其中有LVH者左心室舒张末期内径(LVDd)及左室重量均有明显下降(P<0.05),舒张末期左室后壁厚度(LVPWd)、室间隔厚度(IVSd)及左室重量指数(LVMI)也有明显下降(P<0.01)。结论:缬沙坦在降压的同时可逆转LVH,且安全、有效。
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| 关 键 词： | 高血压 缬沙坦 左心室肥厚 |
| 文章编号： | 1001-7585（2006）09-1009-02 |
| 收稿时间： | 2006-01-13 |
| 修稿时间： | 2006年1月13日 |
Clinical Observation on Treatment Efficacy of Valsartan on Left Ventricular Hypertrophy in Patients with Essential Hypertension |
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| GONG Chengcui,YIN Jianhua,SUN Qingrong.Clinical Observation on Treatment Efficacy of Valsartan on Left Ventricular Hypertrophy in Patients with Essential Hypertension[J].The Journal of Medical Theory and Practice,2006,19(9):1009-1010. |
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| Authors: | GONG Chengcui YIN Jianhua SUN Qingrong |
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| Institution: | The Center Hospital of Binzhou, Shandong Province 251700 |
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| Abstract: | Objective: To study the effect of valsartan on left ventricular hypertrophy in patients with essential hypertension.Methods:58 essential hypertensive patients,including 32 patients with left ventricular hypertrophy were given valsartan orally 80～160 mg per day for eight months.Left ventricular diameter and left ventricular mass index were measured by echoardiography.Results: Systolic blood pressure,diastolic blood pressure significantly decreased (P<0.01).The left ventricular diastolic diameter and left ventricular weight decreased obviously(P<0.05)meanwhile the data of LVPWd,IVSd and LVMI were significantly brought down after Valsartan therapy(P<0.01).Conclusion: Valsartan is an effective drug to reverse left ventricular hypertrophy. |
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| Keywords: | Hypertension Valsartan Left ventrieular hypertrophy |
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