2型糖尿病合并高血压患者胰岛素低抗

The fasting glucose(FBG),TG,CHO,HDL,LDL,ApoA1,ApoB,FIn and insulin sensitiviry index in patients with with type II diabetes mellitus complicated with hypertension were evaluated in the current study.The relationship between hypertension and abnomal level of blood lipid and insulin resistance. 1 Subjects and methods 1.1 Subjects 114 patients with type II diabetes mellitus were selected according to the WHO standards.All the patients were divided into 2 groups,normal blood pressure gr…

Relationship between insulin resistance and blood lipid and sport in patients with type II diabetes mellitus complicated with hypertension

Objective To study the relationship between insulin resistance and blood pressure and blood lipid in patients with type II diabetes mellitus complicated with hypertension.Methods The serum concentration of fasting glucose,insulin,lipids and the level of blood pressure were measured in 56 patients with type II diabetes mellitus complicated with hypertension.Results The insulin sensitivity index(ISI) decreased in patients with type II diabetes mellitus complicated with hypertension compared with the patients with type II diabetes mellitus with normal blood pressure(P< 0.05).A negative correlation with hypertension was found between ISI and SBP,DBP,TG,ApoB in patients with type II diabetes mellitus complicated with hypertension(P<0.05).There was a positive correlation between ISI and HDL in patients with type II diabetes mellitus complicated with hypertension(P<0.05).Conclusion Insulin resistance presents in patients of type II diabetes mellitus complicated with hypertension.Insulin resistance is the major cause of hypertension and lipid metabolic disturbance in patients with type II diabetes mellitus complicated with hypertension.