| 火针治疗中风后痉挛性瘫痪疗效的系统评价和Meta分析 |
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| 引用本文： | 游建宇,饶赟,刘福水,陈梅,方婷,金玉立. 火针治疗中风后痉挛性瘫痪疗效的系统评价和Meta分析[J]. 中国中医基础医学杂志, 2020, 0(2): 229-234 |
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| 作者姓名： | 游建宇 饶赟 刘福水 陈梅 方婷 金玉立 |
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| 作者单位： | 江西中医药大学针灸推拿学院;江西中医药大学附属医院 |
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| 基金项目： | 国家自然科学基金资助项目(81560792)-针刀干预对PI3K/Akt/mTOR信号通路介导颈椎病颈肌细胞自噬与凋亡研究;江西省教育厅科学技术研究项目(重点项目)(GJJ170702)-基于经筋“束骨利关节”研究针刀调筋治骨法对颈椎病软骨细胞的作用机制;江西省卫生计生委科技计划项目(20185514)-针刀疗法经整合素-FAK-MAPK力化学信号通路对颈椎病软骨细胞的影响及机制研究;江西省卫生计生委中医药科研项目(重点课题)(2016Z03)-针刀疗法经整合素β1-FAK力化学信号通路对颈椎病软骨细胞凋亡和自噬的影响研究。 |
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| 摘 要： | 目的:系统评价火针治疗中风后痉挛性瘫痪(spastic paralysis after stroke, SPAS)的疗效与安全性。方法:计算机检索CNKI、万方、CBM、VIP、PubMed及Cochrane library数据库中有关火针治疗SPAS的随机对照试验(randomized controlled trials,RCTs),检索时间为建库至2018年2月,并采用REVMAN5.3软件行Meta分析。结果:最终纳入14篇RCTs共918例患者,Meta分析结果显示,火针组在总有效率、治愈率、Fugl-Meyer运动功能评分、Barthel指数评分、改良Ashworth痉挛量表评分、临床痉挛指数评分和神经功能缺损评分方面均优于对照组。结论:火针治疗SPAS疗效肯定且安全性可靠,由于本研究纳入文献质量低、样本小,仍需高质量和大样本的RCTs加以验证。
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| 关 键 词： | 火针 中风 痉挛性瘫痪 系统评价 META分析 |
Fire Needle Therapy for Spastic Paralysis after Stroke: A Systematic Review and Meta-analysis |
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| Affiliation: | (College of Acupuncture-Moxibustion and Tuina,Jiangxi University of Traditional Chinese Medicine,Nanchang 330004,China;The Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine,Nanchang 330006,China) |
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| Abstract: | Objective: To review systematically the clinical effects and safety of fire needle therapy for spastic paralysis after stroke(SPAS). Methods: We searched six electronic databases to collect randomized controlled trials(RCTs) of fire needle therapy for SPAS published before February 2018. The RevMan 5.3 software was used for meta-analysis. Results: 14 RCTs involving 918 cases were included. The results of Meta-analysis showed that Fire needle therapy group was superior to the control group in improving total effective rate, cure rate, Fugl-Meyer Motor Function Rating Scale, Barthel Index, Modified Ashworth Spasm Scale, Clinical Spasm Index and Neurological Deficit Score. Conclusion: Fire needle therapy is an effective and safe treatment for SPAS. Due to the low quality and small sample size of the included studies, more rigorously designed RCTs with high quality and large-scale are recommended in future. |
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| Keywords: | Fire needle Stroke Spastic Paralysis Systematic review Meta-Analysis |
| 本文献已被 CNKI 维普 等数据库收录！ |
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