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Gastrointestinal complications after kidney transplantation
Authors:Rossella Gioco  Daniela Corona  Burcin Ekser  Lidia Puzzo  Gaetano Inserra  Flavia Pinto  Chiara Schipa  Francesca Privitera  Pierfrancesco Veroux  Massimiliano Veroux
Abstract:Gastrointestinal complications are common after renal transplantation, and they have a wide clinical spectrum, varying from diarrhoea to post-transplant inflammatory bowel disease(IBD). Chronic immunosuppression may increase the risk of post-transplant infection and medication-related injury and may also be responsible for IBD in kidney transplant re-cipients despite immunosuppression. Differentiating the various forms of post-transplant colitis is challenging, since most have similar clinical and histological features. Drug-related colitis are the most frequently encountered colitis after kidney transplantation, particularly those related to the chronic use of mycophenolate mofetil, while de novo IBDs are quite rare. This review will explore colitis after kidney transplantation, with a particular focus on different clinical and histological features, attempting to clearly identify the right treatment, thereby improving the final outcome of patients.
Keywords:Inflammatory bowel disease   Kidney transplantation   Solid organ transplantation   Crohn disease   Ulcerative colitis   Mycophenolate mofetil colitis   Mycophenolate mofetil   Colitis   Cytomegalovirus
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点击此处可从《World journal of gastroenterology : WJG》浏览原始摘要信息
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