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联合草酸铂经肝动脉灌注治疗复发转移性肝癌
引用本文:陈颢,林钧华,宋明志,徐益语,陈震. 联合草酸铂经肝动脉灌注治疗复发转移性肝癌[J]. 肿瘤学杂志, 2001, 7(2): 88-89
作者姓名:陈颢  林钧华  宋明志  徐益语  陈震
作者单位:复旦大学医学院附属肿瘤医院,
摘    要:目的:观察草酸铂(奥沙利铂)在肝动脉中灌注治疗复治转移性肝癌的安全性和疗效。方法:对8例复治的转移性肝癌的患者在肝动脉中灌注200mg奥沙利铂,结果:8例患者中,1例患者达到PR,5例患者NC,2例患者PD;毒副反应均为Ⅰ-Ⅱ度,治疗中未出现肾功能的损伤。结论:奥沙利铂动脉灌注是安全的,初步研究证明在肝动脉中灌注有一定疗效。

关 键 词:奥沙利铂 肝肿瘤 肿瘤转移 介入疗法 肝动脉 治疗
文章编号:1671-170X(2001)02-0088-02
修稿时间:2000-12-04

Intra-arterial Infusion with Oxaliplatin for Cases with Previously Treated Liver Metastasis
CHEN Hao,LIN Jun hua,SONG Ming zhi,et al.. Intra-arterial Infusion with Oxaliplatin for Cases with Previously Treated Liver Metastasis[J]. Journal of Chinese Oncology, 2001, 7(2): 88-89
Authors:CHEN Hao  LIN Jun hua  SONG Ming zhi  et al.
Abstract:[Purpose]To evaluate the effect and safety of intra-arterial infusion with Oxaliplatin for previously treated metastatic liver cancer.[Method]Eight patients with metastatic liver cancer have received intra-arterial 200mg Oxaliplatin once every four weeks.[Results]Each case received twice .In these cases,one reached PR;five,NC and two,PD.One case occurred Ⅱ 0 leucocytopenia,three showed Ⅰ 0~ Ⅱ 0gastrointestinal side effect,one was found Ⅰ 0 hepatic side effect,one appeared Ⅰ 0nerval side effect after two courses treatment.No renal damaged. [Conclusion] It's shown that intra-arterial infusion with Oxaliplatin is safe and effective.
Keywords:Oxaliplatin  liver neoplasms  neoplasm metastasis  interventional therapy  hepatic artery
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