| 盐酸索他洛尔合成工艺条件的分析与优化 |
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| 引用本文： | 金义翠,许同桃.盐酸索他洛尔合成工艺条件的分析与优化[J].齐鲁药事,2004,23(1):43-45. |
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| 作者姓名： | 金义翠 许同桃 |
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| 作者单位： | 1. 南京工业大学制药与生命科学学院,南京,210019
2. 连云港职业技术学院化工系,连云港,222006 |
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| 摘 要： | 本文利用正交实验方法系统地研究了合成盐酸索他洛尔过程中各工艺参数对产品收率的影响 ,得到了最佳工艺条件 ,在此条件下 ,盐酸索他洛尔的收率可达 80 %以上
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| 关 键 词： | 正交实验 盐酸索他洛尔 工艺条件 |
| 文章编号： | 1672-7738(2004)01-0043-03 |
Study on Selection of Synthetic Condition of Sotalol hydrochloride by Orthogonal Test |
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| Jin Yi-cui,Xu Tong-tao.Study on Selection of Synthetic Condition of Sotalol hydrochloride by Orthogonal Test[J].qilu pharmaceutical affairs,2004,23(1):43-45. |
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| Authors: | Jin Yi-cui Xu Tong-tao |
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| Institution: | Jin Yi-cui,Xu Tong-tao 1 |
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| Abstract: | The effects of technical conditions of directive rate sotalol hydrochloride synthesis is process on rare sotalol recovery were systematically studied by orthogonal test.The optimum technical conditions have been found and the recovery of rare sotalol could reach 80% under the conditions. |
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| Keywords: | orthogonal test sotalol hydrochloride technical condensation |
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