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拉莫三嗪对特殊类型癫癎的疗效观察
引用本文:张颖,邓艳春.拉莫三嗪对特殊类型癫癎的疗效观察[J].中华神经外科疾病研究杂志,2014(3):249-251.
作者姓名:张颖  邓艳春
作者单位:[1]第四军医大学西京医院神经内科,陕西西安710032 [2]中铁一局集团西安中心医院神经内科,陕西西安710054
摘    要:目的观察拉莫三嗪(LTG)对特殊类型人群(育龄期女性)部分发作性癫癎患者的疗效和安全性。方法临床确诊的育龄期女性部分性发作癫癎患者90例,LTG单药治疗,定期随访,进行疗效和不良反应的观察。结果 LTG单药治疗育龄期女性部分性发作癫癎患者的有效率在76.7%以上,患者在用药后无一例重度不良反应。结论 LTG对育龄期女性部分性发作癫癎患者的疗效确切,安全性好,对怀孕和生育过程影响较小。

关 键 词:育龄期女性  部分性发作  癫癎  拉莫三嗪

Effect of Lamotrigine on patients with particular of types of epilepsy
ZHANG Ying,DENG Yanchun.Effect of Lamotrigine on patients with particular of types of epilepsy[J].Chinese Journal of Neurosurgical Disease Research,2014(3):249-251.
Authors:ZHANG Ying  DENG Yanchun
Institution:(Department of Neurology, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032;Department of Neurology, Xi'an Central Hospital of China Railway First Group, Xi'an, 710054, China)
Abstract:Objective The efficiency and safety of Lamotrigine (LTG) on particular types of patients (female patients in child-bearing period with partial seizures) are observed.Methods A total of90 female patients in childbearing period with partial seizures confirmed by clinical diagnosis were conducted Lamotrigine monotherapy.Regular follow-ups were conducted to observe the therapeutic effects and adverse reactions.Results The effective rate of Lamotrigine monotherapy on female patients in child-bearing period with partial seizures was more than 76.7%.No patient suffered from severe adverse event after taking the medication.Conclusion LTG has an anti-epileptic effect with good safety for female patients in child-bearing period with partial seizures,while it has little influence on pregnancy and fertility.
Keywords:Female epileptics in child-bearing period  Partial seizure  Epilepsy  LTG
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