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Malaria dispersal among islands: human mediated Plasmodium falciparum gene flow in Vanuatu, Melanesia |
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| Authors: | Lum J Koji Kaneko Akira Tanabe Kazuyuki Takahashi Nobuyuki Björkman Anders Kobayakawa Takatoshi |
| Affiliation: | Department of International Affairs and Tropical Medicine, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan. |
| Abstract: | A comparison of human and Plasmodium falciparum gene flow patterns in the model island system of Vanuatu, the limit of malaria in the Pacific reveals that human movement is essential for long, but not short distance P. falciparum gene flow. This suggests that long distance movement of humans may accelerate the evolution and spread of drug resistance and therefore exacerbate the global malaria problem. |
| Keywords: | Plasmodium falciparum Gene flow Human movement Vanuatu mtDNA control region Remote Oceania |
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