呼吸器引起新生儿呼吸性碱中毒的防治措施

目的 :探讨应用呼吸器引起新生儿呼吸性碱中毒 (呼碱 )的病因及防治措施。方法 :将我院 1992～ 1996年在NICU住院应用呼吸器治疗的 65例新生儿作为甲组 ,1985～ 1989年应用呼吸器治疗的 5 7例新生儿作为乙组进行总结分析。结果 :甲组发生呼碱 11例 (16.92 % ) ,明显低于乙组 (2 1例 ,3 6.84% ) (χ2 =6.3 8,P <0 .0 5 )。结论 :为了进一步降低应用呼吸器引起的碱中毒发生率 ,应根据病情选择合适的吸气峰值 (PIP)和呼吸频率 ,根据病情、血气分析随时调整呼吸器参数 ,降低呼吸频率 ,必要时提高呼气末正压 (PEEP) ,有条件的医院可开展新生儿肺功能检测。

Study on the Prevention and Cure of the Newborn's Respiratory Alkalosis Caused by Ventilator

Objective　To discuss the reasons for newborn's respiratory alkalosis caused by ventilator and its prevention or cure method.Method　65 cases of ventilator using newborns selected in NICU from 1992 to 1996 as the first group.57 cases of ventilator using newborns selected from 1985 to 1989 as the second group.The date of the two groups were compared.Result　The incidence rate of respiratory alkalosis in the first group (11/65,16.92%) was significantly higher than that of the second group(21/57,36.84%)(P<0.05).Conclusion　In order to decrease the respiratory alkalosis caused by ventilator,it is necessary to adjust ventilator setting on time according to the condition of respiratory or increase the value of PEEP.It is suggested that lung function test is necessary to be used.