SARS患者45例临床分析

目的：探讨45例SARS的诊断和治疗方法。方法：对45例SARS病人的临床特点、治疗效果进行了分析。结果：45例均以高热起病，近距离接触过传染源，潜伏期2～15天，45例患者中曾伴有呼吸困难、干咳、乏力、肌肉酸痛。患者随病情进展在进展高峰期肺部X线表现，其中累及两侧肺野为38人，占84．4％，呈实质性病变为31人，占68．9％，死亡为6例，占13．3％。常规抗感染治疗无效，中毒症状明显和肺部阴影扩散时，及时应用持续气道正压通气(EPAP)和皮质激素可有效控制病情发展。结论：该病传染性强，主要经呼吸道传播，常规抗感染治疗无明显效果。肺部阴影增多和呼吸困难加重时。及时应用CPAP和皮质激素是有效的治疗方法。

Clinical analysis of 45 cases of outbreak with SARS

Objective:To study methods of diagnosis and treatment for severe acute respirtory syndrome,outbreak of the illness.Methods:45 cases with SARS were analyzed, and the cases were admitted.Results:Patients were infected by close quarters contacting each other. All patients manifest high fever ,and accompanied by dyspnea, cough ,weakness and muscular soreness. Chest X ray, shadow of lungs were change to severity during the period of tall cusp.6 cases died with sevierity ARDS. Using general antibiotic was of no effect for the illness. Continual positive airway pressure(CPAP)and glucocorticoid was required that can control depravation of the disease when toxicosis symptom of patients was severity and shadow of lungs diffuse more and more. Conclusion: Infectivity of the illness is evidence and spread by airway. Using general antibiotic was of no effect for the illness.Continual positive airway pressure(CPAP)and glucocorticoid are effective for control of the disease.