| 影响血管紧张素Ⅱ作用和合成的新途径及研究进展 |
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| 引用本文： | 张楠,康毅,娄建石. 影响血管紧张素Ⅱ作用和合成的新途径及研究进展[J]. 中国临床药理学与治疗学, 2005, 10(7): 726-729 |
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| 作者姓名： | 张楠 康毅 娄建石 |
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| 作者单位： | 天津医科大学基础医学院药理教研室,天津 300070 |
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| 摘 要： | 肾素-血管紧张素系统(RAS)与多种疾病相关。作为RAS的最终效应途径,血管紧张素II起到了关键作用。本文综述了能够影响其合成及作用的主要途径:血管紧张素II受体拮抗剂(ARB)、糜酶(chymase)抑制剂和晚近发现的ACE2类物质及其相关研究。
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| 关 键 词： | 血管紧张素II ACEI ACE2 ARB 糜酶 |
| 文章编号： | 1009-2501(2005)07-0726-04 |
| 收稿时间： | 2005-04-01 |
| 修稿时间： | 2005-06-02 |
New approach to action and biosynthesis of AngII and on it research |
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| ZHANG Nan,KANG Yi,LOU Jian-shi. New approach to action and biosynthesis of AngII and on it research[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2005, 10(7): 726-729 |
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| Authors: | ZHANG Nan KANG Yi LOU Jian-shi |
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| Affiliation: | Zhang Nan(ZengShu);Kang Yi;Lou JianDan(ShenJiao) |
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| Abstract: | Renin-angiotensin system (RAS) is correlative with many diseases. Angio tensin II (AngII) plays an important role as the final effective approach for RAS. This article reviews the main approach to the action and biosynthesis of AngII: including AngII receptor blocker (ARB), chymase inhibitor and ACE2 which were disscoverd recently. |
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| Keywords: | AngII ACEI ACE2 ARB chymase |
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