某医院消化内科住院患者院内感染危险因素分析及相关管控措施探讨

目的分析增加消化内科住院患者发生院内感染风险的危险因素,并据此探讨相应的管理控制（管控）措施,以更加有效防止消化内科住院患者院内感染的发生。方法回顾性分析2011年4月—2013年4月兴隆县人民医院消化内科收治的1 473例住院患者临床资料,根据患者感染与否分为感染组（135例）及非感染组（1 338例）,对患者院内感染危险因素分别进行单因素分析、logistic多因素回归分析,并根据分析结果总结针对性管控措施。结果该组1 473例消化内科住院患者中院内感染135例,感染率为9.16%;单因素分析显示,性别、年龄（≥60岁）、住院时间、合并糖尿病、肿瘤、联合使用抗生素、使用激素、化疗药物、侵入性操作均与患者院内感染相关（均P〈0.05）;logistic多因素回归分析显示年龄、住院时间、合并基础疾病、侵入性操作及抗生素联合使用为导致患者发生院内感染的独立危险因素。结论消化内科住院患者院内感染是多种因素共同作用的结果,针对各因素采用必要合理的管控措施,可有效降低消化内科患者院内感染的发生率,促进患者康复和预后。

Analysis on risk factors of nosocomial infection among inpatients in gastroenterology department of a hospital and discussion on related control measures

[Objective]To analyze the risk factors of nosocomial infection among inpatients in gastroenterology department,discuss the appropriate control measures,and effectively prevent the nosocomial infection among inpatients in gastroenterology department.[Methods]The clinical data of 1 473 inpatients that were treated in the Gastroenterology Department of Xinglong People＇s Hospital from April 2011 to April 2013 were investigated by the retrospective analysis. The patients were divided into the infection group（135 cases） and the non-infection group（1338 cases） according to whether they have got infection. The risk factors for nosocomial infection were analyzed with univariate analysis and multivariate Logistic regression analysis,and the targeted control measures were carried out based on the results.[Results]There were 135 cases of nosocomial infection among 1 473 inpatients in gastroenterology department,and the infection rate was 9. 16%. The univariate analysis showed that gender,age（ ≥ 60 years）,duration of hospitalization,diabetes,cancer,combined antibiotics,corticosteroids,chemotherapy drugs,and invasive operation were associated with nosocomial infection（ all P 0. 05）. The multivariate Logistic regression analysis that age,duration of hospitalization,underlying diseases, invasive operation and antibiotics combination were the independent risk factor of nosocomial infection.[Conclusion]The nosocomial infection of inpatients in gastroenterology department is resulted from comprehensive function of multiple factors. The necessary and reasonable control measures which are based on the risk factors can effectively reduce the incidence rate of nosocomial infection among inpatients in gastroenterology department,and improve the rehabilitation and prognosis of patients.