冠心病患者冠脉严重程度与冠心病危险因素的相关性分析

目的探讨冠心病患者冠状动脉(冠脉)严重程度与冠心病危险因素的相关性。方法 80例行冠状动脉造影检查者,按病变程度分为观察组(经冠状动脉造影确诊的冠心病患者)和对照组(冠状动脉粥样硬化狭窄程度<10%的患者),各40例。回顾性分析两组患者的临床资料;分析冠心病患者及冠状动脉病变程度的相关因素。结果冠心病重度病变患者吸烟例数少于中度和轻度病变患者, 2型糖尿病、高血压例数多于轻度病变患者, LVEF异常例数少于轻度病变患者,差异具有统计学意义(P<0.05)。Logistic分析结果显示,吸烟、2型糖尿病、高血压与冠状动脉病变程度相关(P<0.05)。结论 2型糖尿病、高血压、吸烟、男性为冠心病的危险因素,且冠状动脉病变程度与患者的左心功能降低有关,由此,积极控制与冠状动脉病变关系更大的冠心病危险因素,可以早期防治冠心病进一步恶化的发生,减少冠状动脉狭窄与后期严重并发症的出现。

Correlation analysis between between severity of coronary artery disease and risk factors of coronary heart disease in patients with coronary heart disease

Objective To discuss the correlation between between severity of coronary artery disease and risk factors of coronary heart disease in patients with coronary heart disease. Methods A total of 80 patients undergoing coronary angiography were divided into observation group(patients with coronary artery disease confirmed by coronary angiography) and control group(patients with coronary artery stenosis <(10%) by the degree of pathological changes, with 40 cases in each group. The clinical data of the two groups of patients were retrospectively analyzed. The related factors of coronary heart disease and severity of coronary artery disease were analyzed. Results The number of smoking in patients with severe coronary heart disease is less than that in patients with moderate and mild coronary heart disease, the number of type 2 diabetes mellitus and hypertension is more than that in patients with mild coronary heart disease, and the number of abnormal LVEF is less than that in patients with mild coronary heart disease. The difference was statistically significant(P<0.05). The results of Logistic analysis showed that smoking, type 2 diabetes mellitus and hypertension were correlated with the degree of coronary artery disease(P<0.05). Conclusion Type 2 diabetes, hypertension, smoking, and men are risk factors for coronary heart disease, and the degree of coronary artery disease is correlated to the reduction of left heart function in patients. Therefore, actively controlling the risk factors of coronary heart disease, which are more related to coronary artery disease, can prevent and treat the further deterioration of coronary heart disease in early stage, and reduce the occurrence of coronary artery stenosis and serious complications in later stage.