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褪黑素与癫癎
引用本文:温晓妮,黄远桂,王津存. 褪黑素与癫癎[J]. 中国临床神经科学, 2005, 13(3): 319-321
作者姓名:温晓妮  黄远桂  王津存
作者单位:第四军医大学西京医院,神经内科癫癎研究中心,710032
摘    要:褪黑素(melatonin,MT)是松果体合成和分泌的一种神经内分泌激素,不仅参与生物周期性节律、神经-内分泌-免疫调节、镇静、催眠等,而且在Alzheimer病、失眠、抑郁症等多种疾病中具有治疗作用.同时,在许多有关癫癎的临床和动物实验研究中发现MT有抗癎和促癎的双重作用.本文从MT的生理活性入手,就近5年来有关MT的抗癎和促癎作用及可能机制做一综述.

关 键 词:褪黑素  癫癎  治疗
文章编号:1008-0678(2005)03-0319-03
修稿时间:2004-09-20

Melatonin and Epilepsy
WEN Xiao-ni,HUANG Yuan-Gui,WANG Jin-Cun. Melatonin and Epilepsy[J]. Chinese Journal of Clinical Neurosciences, 2005, 13(3): 319-321
Authors:WEN Xiao-ni  HUANG Yuan-Gui  WANG Jin-Cun
Affiliation:WEN Xiao-Ni,HUANG Yuan-Gui,WANG Jin-Cun Research Center of Epilepsy,Department of Neurology,Xijing Hospital,the Fourth Military Medical University of Chinese PLA,Xi'an 710032,China
Abstract:Melatonin is a hormone synthesized and secreted by the pineal gland. Moreover,melatonin shows a daily rhythm of synthesis. Besides its functions in many behavioral processes including those related to anxiolytic ,sedative and hypnotic properties,melatonin has anticonvulsant and proconvulsive activities. From double activities,this article reviewed melatonin in the recent five years.
Keywords:melatonin  epilepsy  treatment
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