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尼莫地平注射液细菌内毒素检查法研究
引用本文:郭维儿. 尼莫地平注射液细菌内毒素检查法研究[J]. 中国药师, 2004, 7(9): 709-710
作者姓名:郭维儿
作者单位:浙江医药高等专科学校,宁波,315010
摘    要:目的:建立尼莫地平注射液细菌内毒素检查方法.方法:采用<中国药典>2000年版附录细菌内毒素检查法.结果:尼莫地平注射液在稀释至8倍时检查细菌内毒素可完全排除干扰因素的影响.结论:细菌内毒素检查法可代替家兔热原检查法.进行尼莫地平注射液中内毒素的检查.

关 键 词:尼莫地平注射液  细菌内毒素检查  干扰试验  鲎试验
文章编号:1008-049X(2004)09-0709-03
修稿时间:2003-11-10

Study on Bacterial Endotoxin Test for Nimodipine Injection
Guo Weier. Study on Bacterial Endotoxin Test for Nimodipine Injection[J]. China Pharmacist, 2004, 7(9): 709-710
Authors:Guo Weier
Abstract:Objective: To establish a method for examination of bacterial endotoxions of nimodipine injection.Method: The bacterial endotoxion test approved by Chinese Pharmacopoeia (edition 2000) was used.Result: The bacterial endotoxins test showed neither inhibition nor enhancement when nimodipine injection was diluted up to 8 stimes.Conclusion: The technique of TAL test can be used as an alternative method in the rabbit pyrogen test for nimodipine injection.
Keywords:Nimodipine injection  Bacterial endotoxin test  Interfere test  Limulus test  
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