肝硬化门脉高压患者入肝血流的超声评价

目的观测肝硬化门脉高压患者入肝血管(肝动脉、门静脉)血流动力学,探讨其与Child-Pugh肝功能分级、临床预后的关系.方法应用彩色多普勒超声分别检测35例正常健康人和37例肝硬化门脉高压患者的人肝血管的血流参数,分析肝硬化门脉高压入肝血管血流动力学参数与肝硬化分级关系.结果肝硬化门脉高压患者门静脉内径增宽,血流速度下降,充血指数增高,肝动脉血流阻力增高,与对照组有明显差异;肝硬化门脉高压患者Child-Pugh肝功能分级与门静脉内径无显著差异(P＞0.05),Child C级门静脉血流量显著减少,Child肝功能分级与门静脉的充血指数有关.结论测定入肝血管血流动力学参数有助于判断肝硬变门脉高压症的预后,为临床诊治提供依据.

Ultrasonographic evaluation of hepatic artery and portal vein in patients with cirrhosis and portal hypertension

Objective To observe the hemodynamic changes in hepatic artery and portal vein in the patients with ciirhosis and portal hypertension and study the relationship between the hemodynamic changes and Child-Pugh grade. Methods Hemodynamics of hepatic artery and portal vein in 35 healthy controls and 37 patients with liver cirrhosis were investigated, from which the relationship of hemodynamics and the grade of cirrhosis was discussed. Results Compared to normal control, the diameter of portal vein was significantly widened, the blood flow velocity of the portal vein was significantly decreases, resistance index (RI) of the hepatic artery and congestion index (CI) of the portal vein were significantly increased. There was no significant difference between the diameter of portal vein and all Child grade groups (A, B, C) (P>0.05). However, the portal blood flow volume was significantly decreased in Child's C cirrhosis. Child grade is related to PCI of the portal vein. Conclusion The hemodynamic changes of hepatic artery and portal vein in the patients with cirrhosis and portal hypertension can provide useful information in assessing prognosis.