肱骨三维模型的构建及其生物力学意义

背景肱骨骨折治疗方法多样,但是也常常遗留严重的并发症如骨不连等,尝试采用新的生物力学分析手段,以期为肱骨骨折、骨不连的功能预后提供新思路.目的构建肱骨三维模型,并探讨其相关的生物力学意义.设计构建肱骨三维有限元模型.单位一所军医大学的附属医院骨科和一所大学生命科学与生物工程学院共同开展.材料实验于2002-04/2004-04在上海长海医院和上海同济大学生命科学实验室完成,选择典型的成年男性湿肱骨标本一根.方法选择湿肱骨标本行CT成像得到肱骨每层横截面图像,采用大型有限元分析软件ANSYS5.6建立肱骨三维模型.主要观察指标①构建的肱骨三维有限元模型的生物力学特性.②与实际临床的区别以及主要的相同点.结果所构建肱骨三维模型,逼真反映肱骨真实解剖形态及生物力学行为,同时与CT切片图相对比以判断其精确性.结论肱骨三维有限元模型的构建,可以为肱骨正常力学行为以及骨折后内固定的力学基础研究提供精确模型.

Construction of humeral three-dimensional model and its biomechanical significance

BACKGROUND: Various therapies can be used to treat humeral fracture,but serious complications like bone disunion, etc. Are often left over. New biomechanical analytical methods are tried to be applied to provide new approaches for the functional prognosis in humeral fracture and bone disunion.OBJECTIVE: To construct humeral three-dimension model to explore its correlated biomechanical significance.DESIGN: To construct humeral three-dimension finite element model. SETTING: Department of orthopedics of a military medical university-affiliated hospital and institute for biological science and bioengineering of a university.PARTICIPANTS: The study was conducted in Shanghai Changhai Hospital and the Laboratory of Biological Science of Shanghai Tongji University. One piece of typical adult wet humerus sample was selected.INTERVENTIONS: Cross section image of each humeral layer was obtained from the selected wet humerus sample by CT scanning, and humeral three-dimensional model was constructed by large finite element analytic software ANSYS5.6.MAIN OUTCOME MEASURES: ① Biomechanical features of the constructed humeral three-dimension mode; ② Differences from clinical reality and key similarities.RESULTS: The constructed humeral three-dimensional model vividly reflected the true humeral anatomic morphology and biomechanical behavior. Its precision was judged by the comparison with CT image.CONCLUSION: The construction of humeral three-dimension finite element model provides a precise model for the researches of normal humeral mechanical behavior and the basic mechanics of internal fixation after fracture.