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Analysis of the essential oil from the aerial parts of Psoralea pubescence (Miq.) Standl and its antibacterial activity
Authors:Hesham El-Seedi  Mervat Zayed  Shimaa Roshdy  Mohamed Salem  Mohamed Hawata  Farag El-Essawy  Mai El-Barbary  Salah El-Kousy
Institution:(1) Division of Pharmacognosy, Department of Medicinal Chemistry, Biomedical Centre, Uppsala University, Box 574, Uppsala, 751 23, Sweden;(2) Department of Chemistry, Faculty of Science, El-Menoufia University, Shebin El-Kom, 32512, Egypt;(3) Genetic Engineering and Biotechnology Research Institute, El-Menoufia University, Shebin El-Kom, 32512, Egypt
Abstract:The essential oil from aerial parts of Psoralea pubescence (Miq.) Standl (Leguminoseae) was analyzed by gas chromatography (GC) and GC/mass spectroscopy systems. The major components identified were psoralen (24.8%), bakuchiol (21.3%), β-caryophyllene (8.5%), germacrene D (6.8%), and α-humulene (4.6%). The major volatiles released by β-glucosidase treatment of the aqueous plant residue were δ-pinene (28.3%), germacrene D (13.6%), and tricyclene (10.2%). The oil showed significant antibacterial activity against Staphylococcus aureus, Escherichia coli, Klebsiella pneumonia, and Pseudomonas aeruginosa, while the β-glucosidase-liberated fraction was inactive.
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