| 三维适形放射治疗胰腺癌临床疗效观察 |
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| 引用本文： | 陈年春,周丽华,黎世秋. 三维适形放射治疗胰腺癌临床疗效观察[J]. 肿瘤基础与临床, 2007, 20(6): 524-525 |
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| 作者姓名： | 陈年春 周丽华 黎世秋 |
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| 作者单位： | 连云港市第一人民医院放疗科,江苏,连云港,222002;连云港市第一人民医院放疗科,江苏,连云港,222002;连云港市第一人民医院放疗科,江苏,连云港,222002 |
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| 摘 要： | 目的应用三维适形放射治疗技术治疗胰腺癌，评价其疗效及毒副反应。方法24例胰腺癌全部采用三维适形放射治疗，常规分割，总剂量60～70Gy，42～49d。结果治疗结束2～3个月后评价近期疗效，CR7例，占29．2％；PR14例，占58．3％；NC3例，占12．5％。总有效率（CR＋PR）达87．5％。中位生存期13个月，1年生存率58．3％。毒副反应主要为恶心、呕吐及白细胞减少，均可耐受。结论三维适形放射治疗胰腺癌近期效果满意，毒副反应轻，为失去手术机会的胰腺癌患者提供了一种有效治疗手段。
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| 关 键 词： | 胰腺癌 放射治疗 三维适形 |
| 文章编号： | 1673-5412（2007）06-0524-02 |
| 收稿时间： | 2007-05-23 |
| 修稿时间： | 2007-05-23 |
A Clinical Observation of Three Dimensional Conformal Radiotherapy for Pancreatic Cancer |
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| Chen Nianchun, Zhou Lihua, Li Shiqiu. A Clinical Observation of Three Dimensional Conformal Radiotherapy for Pancreatic Cancer[J]. Journal of Basic and Clinical Oncology, 2007, 20(6): 524-525 |
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| Authors: | Chen Nianchun Zhou Lihua Li Shiqiu |
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| Abstract: | Objective To evaluate the efficacy and toxicity of three dimensional conformal radiotherapy(3-DCRT) for pancreatic cancer.Methods Twenty-four patients with pancreatic cancer received 3-DCRT with conventional fraction,2.0 Gy per fraction,five fractions per week.The total dose was 60-70 Gy for 42-49 days.Results The complete response(CR) rate was 29.2%(7/24),the partial response(PR) rate was 58.3%(14/24) and the no change(NC) rate was 12.5%(3/24) in two or three months after 3-DCRT.The overall response(CR PR) rate was 87.5%.The median survival duration and 1-year survival rate were 13 months and 58.3% respectively.The treatment was tolerated well.The side effects were observed as nausea,vomiting and leuxocytopenia.Conclusions 3-DCRT is a safe and effective treatment of patients with advanced pancreatic cancer.The better local control rate and longterm survival rate can be expected. |
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| Keywords: | pancreatic cancer radiotherapy three dimensional conformal radiotherapy |
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