| 甲状腺肿瘤细胞增殖活性的研究 |
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| 引用本文： | 安丰奇,罗英伟.甲状腺肿瘤细胞增殖活性的研究[J].中华实验外科杂志,1995,12(6):364-365. |
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| 作者姓名： | 安丰奇 罗英伟 |
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| 作者单位： | 中国医科大学第一临床学院普外，中国医科大学肿瘤研究所 |
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| 摘 要： | 应用免疫组织化学方法检测４０例不同类型甲状腺肿瘤中增殖细胞核抗原（ＰＣＮＡ／Ｃｙｈｃｌｉｎ）的表达，结果表明：ＰＣＮＡ的阳性表达率在结节性甲状腺肿为１．１３％，甲状腺瘤为６．１５％，乳头状癌为６．５５％，滤泡癌６．６７％，未分化癌为２３％，提示ＰＣＮＡ阳性反应可以反映甲状腺瘤的临床生物学行为。
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| 关 键 词： | 甲状腺肿瘤 增殖细胞 核抗原 免疫组化 |
Proliferating cell nuclear antigen expres-sion on human thyroid neoplasms |
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| An Feng-qi,Luo
Ying-wei,Li Xin,et al..Proliferating cell nuclear antigen expres-sion on human thyroid neoplasms[J].Chinese Journal of Experimental Surgery,1995,12(6):364-365. |
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| Authors: | An Feng-qi Luo
Ying-wei Li Xin |
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| Institution: | An Feng-qi,Luo
Ying-wei,Li Xin,et al. First Clinical Col-lege,China Medical University 110001. |
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| Abstract: | 40 cases
of thyroid neoplasm of varioustypes were investigated immunohis-tochemically using ABC
technique with anti-proliferating cell nuclear antigen(PCNA/cy-clin)antibody. The result showed
that differ-entiated carcinoma displayed a significantlyhigher percentage(P<0.01)of
PCNA-positivecell(23.00%),than follicular carcinoma(6.67%),papillary carcinoma(6.
50%)adeno-ma(6.15%)and nodular goiter(1. 13%).Thestudy suggests the PCNA is an important
clin-ical biologic index in the evaluation of the thy-roid neoplasms. |
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| Keywords: | thyroid neoplasm proliferat-ingcell nuclear antigen immunohis-tochemistry |
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