局部应用硼砂霜治疗皮肤真菌病573例疗效观察

本文报告了硼砂在试管中的抗真菌实验及临床治找的结果.573例皮肤真菌病分组采用20多及15男硼砂霜治东结果如下:20%和15%硼砂霜的治愈率分别为66.36%及75.41%;有效率为83,48%及92,50%.两种硼砂霜的疗效研究对比发现,15解硼砂霜较20多为优(P<0.005),两者的副作用皆较小.我们发现硼砂在试管中具有较强的抗真菌作用,对红色毛癣菌,石膏样毛癣菌及紫色毛癣菌的最低抑菌浓度为0.05-0.1%,对白念珠菌及絮状表皮癣菌为0.5-1%.

Observation of the therapeutic effect of topical application of borax cream in treating 573 cases of dermatomycoses

The results of clinical therapeutic trials and fungistatic tests of borax is vitro were reported, 573 cases of dermatomycoses were treated with 20% borax cream and 15% borax cream. The results. were as follows:the curing rates of 20% borax cream and 15% borax cream were 66.36% and 75.41% and the effective rates were 83.48% and 92.50% respectively.The therapeutic response of 15% borax cream was better than that of 20% borax cream (P<0.005). The side-effects-of both borax creams were rare and slight. We found that borax had relatively strong fungistatic action on dermatophytes in vitro.The minimal inhibitory concentration (MIC) of the aqueous solution of borax for T. rubrum, T. gypseum and T. violaceum was 0.05-0.1%,and the MIC for C. albicans and E. floccosum was 0.5-1%.